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临时周围神经刺激的作用机制

Alaa Abd-Elsayed¹, Sumedha Attanti², Meredith Anderson²

¹Department of Anesthesiology and Pain Management, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.

Current pain and headache reports

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概括

周围神经刺激 (PNS) 通过使用电脉冲来阻止疼痛信号,为疼痛管理提供了一种新的方法. 这种技术有效治疗各种慢性疼痛和急性术后疼痛.

科学领域:

神经学神经学
疼痛管理疼痛管理
生物医学工程生物医学工程

背景情况:

外围神经刺激 (PNS) 是一种使用外围神经电刺激来抑制疼痛信号传输的技术.
它用于慢性难治疼痛,术后/创伤性疼痛,头痛,面部疼痛,骨盆疼痛,胸壁疼痛以及残留/幻肢疼痛.

研究的目的:

审查外周神经刺激 (PNS) 在疼痛管理中的应用和机制.
探索近期使用PNS治疗急性手术后疼痛 (不到60天).

主要方法:

对外围神经刺激技术及其有效性的现有文献的审查.
对中枢和外围通路中PNS的建议作用机制的分析.

主要成果:

PNS有效治疗各种疼痛状况,包括慢性和急性疼痛.
最近的应用表明,PNS对急性术后疼痛有益.
据信,PNS通过中心抑制α-delta和C纤维,并通过外围调节炎症媒介来起作用.

结论:

周围神经刺激是管理各种疼痛状况的多功能治疗选择.
它的双重中央和外围机制有助于其在减轻疼痛方面的有效性.

关键词:

中枢神经系统中枢神经系统疼痛疼痛疼痛疼痛周围神经的刺激.周边路径的路径.

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