基于TEG的输血协议与减少血液产品的使用有关,而不会增加血液瘤的风险
Brittany Bromfield1, Roberto Tellez1, Dempsey L Hughes2
1Department of Internal Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Hepatology communications
|October 27, 2023
概括
一个新的血栓凝聚成像 (TEG) 输血协议,用于经过抛物线治疗的肝硬化患者,显著减少了血液制品的使用. 这种方法成功地减少了输血,而没有增加对后血瘤 (PPH) 的发生率.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 输血医学 输血医学
- 干预性胃肠病学 干预性胃肠病学
背景情况:
- 肝硬化患者接受形手术时面临出血风险,需要输血血液产品.
- 血小板造影 (TEG) 用于指导输血决策.
- 宫后血 (PPH) 是一个潜在的并发症.
研究的目的:
- 评估基于TEG的输血协议对体前血液产品利用的影响.
- 在实施TEG协议后评估PPH的发病率.
主要方法:
- 一项对483名肝硬化患者进行的雄心勃勃的分析,其中1281名患者接受了表 (2017-2021年).
- 在2019年5月实施TEG引导的输血协议.
- 在TEG前和TEG后的协议队列中,血液产品的使用和PPH发生率的比较.
主要成果:
- 血制品输血在协议实施后显著下降,从228个产品减少到49个产品 (p<0.001).
- 观察到与此相关的成本节约.
- 每个队列中的1名患者患有PPH,没有增加发病率.
结论:
- 一个以TEG为基础的输血协议有效地减少了肝硬化患者的血液产品利用率.
- 协议的实施并没有导致PPH的发病率增加.
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