在门诊血压监测参数中的种族差异
Swati Sakhuja1, Byron C Jaeger2, Yuichiro Yano3,4
1University of Alabama at Birmingham, Birmingham, Alabama.
Blood pressure monitoring
|October 27, 2023
概括
与白人成年人相比,黑人成年人表现出更高的睡眠系统血压 (SBP) 负载和清醒透气血压 (DBP) 变化,包括平均真实变化 (ARV) 和峰值增加. 这些门诊血压监测 (ABPM) 发现持续独立于平均血压水平.
科学领域:
- 心血管健康 心血管健康
- 高血压研究 高血压研究
- 健康方面的种族差异.
背景情况:
- 门诊血压监测 (ABPM) 提供了广泛的数据,超出了平均静缩和静缩血压 (SBP和DBP) 的范围.
- 现有的研究表明,与白人成年人相比,黑人成年人的平均SBP和DBP高.
- 关于非平均ABPM参数与心血管风险相关的种族差异的数据有限.
研究的目的:
- 调查黑人和白人成年人之间的各种ABPM衍生参数的种族差异.
- 确定特定的ABPM指标,超出平均BP,可能因种族而异,并导致心血管风险差异.
主要方法:
- 利用了来自五项美国研究的数据,其中包括2580名接受ABPM的参与者.
- 计算SBP和DBP水平 (平均值,负载,峰值) 和变化 (平均真实变化[ARV],峰值增加) 的指标.
- 进行了多变量调整,以考虑潜在的混因素.
主要成果:
- 黑人参与者 (58.6%) 平均年龄大于白人参与者 (41.4%).
- 调整后的分析显示,黑人与白人的参与者睡眠时SBP负荷 (5.7%) 和DBP负荷 (2.7%) 较高.
- 与白人参与者相比,黑人参与者也表现出更高的清醒DBPARV和峰值DBP增加.
结论:
- 与白人成年人相比,黑人睡眠时的SBP负荷和特定的清醒时的透析血压 (DBP) 参数 (ARV,峰值增加) 较高.
- 这些ABPM参数的差异是独立于平均血压观察到的.
- 这些发现突出了潜在的种族特异性ABPM标志物,有助于黑人成年人的心血管风险.
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