呼吸道异常的发生率在儿童与骨突症
Dana Eitan1, Aditi Bhuskute2, Patrick Scheffler2
1Creighton University School of Medicine.
The Journal of craniofacial surgery
|October 27, 2023
概括
患有综合性关节缩症的儿童有明显更高的呼吸道异常率,包括门缩和气管切除. 建议对这些患者进行常规的呼吸道评估.
科学领域:
- 儿科手术 儿科手术
- 遗传学 是一个遗传学.
- 肺部病理学 肺部病理学
背景情况:
- 头骨突症是一种导致头骨过早融合的疾病,在儿童中经常出现呼吸道异常.
- 以前的研究表明,综合征性关节缩症和呼吸道问题之间存在联系,但缺乏大规模数据.
研究的目的:
- 通过使用国家住院患者数据库,调查综合性关节突变和呼吸道异常之间的关联.
- 为了比较特异性气道诊断和气管切除术在综合征与非综合征性头骨突症患者中的发生率.
主要方法:
- 使用2016年医疗保健成本和利用项目儿童住院患者数据库进行的回顾性队列研究.
- 分析人口统计数据,呼吸道诊断和4914名患有骨突症的儿童的并发症.
主要成果:
- 综合性头骨突症患者 (136名儿童) 显示,门缩的发生率显著更高 (31%对2.5%).
- 综合症患者更有可能患有喉发,气管狭窄和气管发.
- 气管切除术的发生率是综合征性突症患者的5.84倍 (28.4%对比4.6%).
结论:
- 综合性关节突变症与较高的门缩和其他呼吸道异常发生率密切相关.
- 对于所有综合性关突症患者来说,需要进行常规的呼吸道评估.
- 对于非综合征性关突症患者,有气消化系统症状的患者,也建议对呼吸道进行警评估.
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