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Updated: Jul 12, 2025

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由BRME1进行的BRCA2-HSF2BP寡合环分解促进同源重组

Rania Ghouil1, Simona Miron1, Koichi Sato2

  • 1Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198 Gif-sur-Yvette, France.

Science advances
|October 27, 2023
PubMed
概括

HSF2BP-BRME1复合体调节BRCA2,这是同源重组 (HR) DNA修复中的关键蛋白质. BRME1防止HSF2BP降解BRCA2,确保有效的DNA修复和促进HR.

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