跨导管大动脉置换后的长期结果:卡普兰-梅尔衍生数据的元分析
Junichi Shimamura1, Sho Takemoto2, Shinichi Fukuhara3
1Department of Surgery, Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
概括
透气管大动脉置换术 (TAVR) 后的长期结果显示,10年生存率为12.1%. 结构的恶化 (SVD) 是低的,在8年内85%的SVD自由.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 心脏门疾病 心脏门疾病
背景情况:
- 过导管大动脉置换 (TAVR) 是手术AVR的替代方案.
- TAVR的长期结果尚未完全确定.
研究的目的:
- 使用元分析分析TAVR后的长期结果.
- 评估生存率和没有结构门恶化 (SVD) 的情况.
主要方法:
- 对11项随访时间≥8年的研究进行了元分析.
- 包括5458名患者;评估的胸部外科医生协会 (STS) 预测的死亡风险 (PROM).
- 对中等/高手术风险患者的子组分析.
主要成果:
- 10年生存率为12.1%±2.0%. 这是一个很好的结果.
- 在8年内,SVD无病率为85.1%±3.1%.
- 在中高风险子组中观察到类似的结果.
结论:
- TAVR的存活率有限,在10年内死亡率为~88%.
- 这种SVD是罕见的,并且似乎没有影响生存率.
- 需要对年轻,风险较低的患者进行进一步的研究.
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