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Updated: Jul 12, 2025

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RBPMS通过RNA替代拼接来调节心肌细胞收缩和心脏功能

Peiheng Gan1, Zhaoning Wang1,2, Svetlana Bezprozvannaya1

  • 1Department of Molecular Biology, Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390, USA.

Cardiovascular research
|October 27, 2023
PubMed
概括

多重拼接的RNA结合蛋白 (RBPMS) 对成人心脏功能至关重要. 失去RBPMS会通过改变sarcomeric基因拼接导致严重的心脏缺陷,导致扩张性心肌病和早期死亡.

关键词:
心肌细胞收缩的收缩扩展性心肌病变性是指扩展性心肌病变性.在Pdlim5中,你会看到Pdlim5.这是一种RNA结合蛋白.标题: 一个人的心

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