饮用水的化:基因毒性控制和三甲形成之间的权衡
Chao Fang1, Wenyuan Yang1, Nannan Lu2
1State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China; Ministry of Education Key Laboratory of Yangtze River Water Environment, Tongji University, Shanghai 200092, China.
化可显著降低水的基因毒性30-90%,主要是通过分解未知的消毒副产品 (DBPs). 然而,这种方法增加了三甲 (THM) 的形成,强调需要监测整体水的毒性.
科学领域:
- 环境化学环境化学
- 水处理 处理水的方法
- 毒理学 毒理学 毒理学
背景情况:
- 消毒副产品 (DBPs) 在化水过程中形成,对健康构成风险.
- 化的pH值是影响DBP形成和相关的基因毒性的一个关键因素.
- 现有的法规往往侧重于特定的DBP,如三甲 (THM),可能会忽视其他有毒化合物.
研究的目的:
- 为了研究化pH对水基因毒性的影响.
- 确定已知和未知DBPs对整体基因毒性的贡献.
- 评估性化在减少基因毒性的有效性及其对THM形成的影响.
主要方法:
- 水样在不同的pH值 (6.5至8.5) 处被化.
- 用生物测试评估了基因毒性.
- 测量DBPs的度,包括THMs,被量化.
- 皮尔森的相关性分析被用来将基因毒性与水成分联系起来.
主要成果:
- 将化pH值从6.5提高到8.5将遗传毒性降低了30-90%.
- 测量的DBP对整体基因毒性贡献不到5%,未知DBP是主要关注点.
- 性化增强了THM的形成,特别是在用颗粒状活性碳处理的水中.
- 化有机物和可溶性微生物副产品被确定为基因毒性化合物的可能来源.
结论:
- 化是一种有效的策略,通过分解未知的DBPs来降低水的基因毒性.
- 由于与基因毒性不一致的趋势,THM是整体DBP毒性的不充分指标.
- 评估散装水的毒性,超出监管的DBP,对于全面的风险评估至关重要.
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