在患有转移性胃肠道筋瘤的患者中,激酶突变和伊马替尼布反应

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Updated: Jul 12, 2025

Molecular and Immunologic Techniques in a Genetically Engineered Mouse Model of Gastrointestinal Stromal Tumor
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Molecular and Immunologic Techniques in a Genetically Engineered Mouse Model of Gastrointestinal Stromal Tumor

Published on: May 2, 2022

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Michael C Heinrich1, Christopher L Corless1, George D Demetri1

  • 1From the Oregon Health and Science University Cancer Institute, Oregon Health and Science University, and Portland Veterans Affairs Medical Center, Portland, OR; Dana-Farber Cancer Institute and Harvard Cancer Center, Boston, MA; Fox-Chase Cancer Center, Philadelphia, PA; University of Turku, Turku; University of Helsinki, Helsinki, Finland; and Novartis Oncology, Basel, Switzerland.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
|October 27, 2023
PubMed
概括

具有特定KIT突变的胃肠道 stromal 瘤 (GIST),特别是外显子11,对伊马替尼治疗有更好的反应. 了解这些突变有助于预测高级GIST患者的结果.

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