葡萄糖耐受性状态与肥胖成年人高强度运动后认知功能的改善有关
Gregory N Ruegsegger1, Emily R Ekholm1, Chandler E Monroe1
1Department of Health and Human Performance, University of Wisconsin-River Falls, A173 Falcon Center, 410 S. 3rd St., River Falls, WI, 54022, United States.
Physiology & behavior
|October 27, 2023
概括
高强度运动有利于瘦身和正常耐葡萄糖的肥胖成年人的认知. 然而,葡萄糖耐受性受损阻碍了这些认知收益,将它们与炎症和胰岛素水平联系起来.
科学领域:
- 运动生理学 运动生理学
- 神经科学是一个神经科学.
- 代谢健康 代谢健康
背景情况:
- 肥胖,胰岛素抵抗和炎症与认知能力下降有关.
- 急性炼通常会改善瘦身个体的认知能力.
- 肥胖和胰岛素抵抗对运动诱导的认知变化的影响尚不清楚.
研究的目的:
- 研究肥胖和葡萄糖耐受性受损如何影响高强度有氧运动后的认知功能.
- 为了比较对运动的认知反应,瘦身,肥胖的正常葡萄糖耐受性和肥胖的葡萄糖耐受性受损的个体.
主要方法:
- 49名成年人 (瘦身,肥胖-NGT,肥胖-IGT) 接受了高强度间歇运动.
- 在运动前和运动后评估认知功能.
- 采集血液样本以测量炎症性细胞因子和胰岛素水平.
主要成果:
- 精瘦和肥胖NGT组的认知功能有所改善,但肥胖IGT组没有.
- 在口服葡萄糖耐受性测试中,认知改善与2小时后的葡萄糖水平负相关.
- 肥胖IGT患者炼后持续升高的IL-6和CRP水平与较差的认知变化有关.
结论:
- 急性运动的认知益处取决于葡萄糖耐受性,而不仅仅是体重或身体成分.
- 葡萄糖耐受性受损与持续的炎症和运动所带来的认知效益降低有关.
相关概念视频
Overview of Carbohydrate Metabolism
1.1K
Carbohydrate metabolism is a fundamental biochemical process that ensures a constant supply of energy to living cells. The most important carbohydrate is glucose, which can be broken down via glycolysis to enter into the Krebs cycle and eventually lead to the production of ATP through oxidative phosphorylation.
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
1.1K
Diabetes: Symptoms, Diagnosis, and Complications
557
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
557
Glucose Homeostasis: Regulation of Blood Glucose
1.7K
Carbohydrates consumed through foods are converted into glucose, a crucial energy source for the body. In the prandial state, high blood glucose levels stimulate the secretion of insulin from the pancreas. Insulin inhibits hepatic glucose production and stimulates glucose uptake and metabolism by muscle and adipose tissue. The excess glucose is converted into glycogen and stored in the liver and muscles.
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
1.7K
Cognitive Development During Adulthood
125
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
125


