对评分吸入器技术的方法进行系统审查
Ruth De Vos1, Alexander Hicks2, Mitch Lomax3
1Portsmouth Technology Trials Unit, Portsmouth Hospitals University NHS Trust, UK; University of Portsmouth, School of Sport, Health and Exercise Science, UK; Department of Respiratory Medicine, Portsmouth Hospitals University NHS Trust, UK.
Respiratory medicine
|October 27, 2023
概括
吸入器技术评分方法各不相同,大多数研究都使用了简单的检查清单. 需要有效的工具来准确测量吸入器技术,以更好地控制疾病.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 制药科学 制药科学
- 临床药房 临床药房
背景情况:
- 低效的吸入器技术是临床实践中的一个重要问题,导致药物不充分地输送到呼吸道和不理想的疾病管理.
- 存在许多吸入器设备,每个都有独特的功能,旨在缓解技术相关的问题.
- 评估吸入器技术对于优化吸入药物患者治疗结果至关重要.
研究的目的:
- 系统地审查和评估用于研究中评估吸入器技术的各种评分方法.
- 确定最常见的评分方法并分析它们的特征和局限性.
- 突出了对可靠的吸入器技术评估的验证仪器的需求.
主要方法:
- 进行了系统的文献搜索,并对审查协议进行了前性注册.
- 由于研究设计和数据的异质性,使用了叙事综合方法来呈现研究结果.
- 包括的研究被选,最终有77篇文章被选中进行分析.
主要成果:
- 最常见的评分方法包括在吸入器技术检查清单中 (在77%的文章中使用) 每步评分1分,但解释指南有限.
- 评分方法有很大的差异,包括分级,百分比/比率表达,点扣除和步骤加权.
- 吸入器技术检查清单显示,在不同设备类型的步骤数量 (5-19) 和内容方面存在实质性的异质性.
- 只有5%的评估措施已经经历了必要的步骤,以便在现实世界中应用规模的发展.
结论:
- 目前用于评分吸入器技术的方法高度异质,缺乏标准化.
- 对于一个可靠和验证的工具来准确测量吸入器技术,有明显的需求.
- 需要开发和验证一个强大的吸入器技术评分工具,以改善患者的治疗结果和疾病控制.
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