连接组织疾病的儿童的门节约根置换:长期风险的大动脉事件的风险
Ilkun Park1, Ji-Hyuk Yang1, Kiick Sung1
1Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
The Journal of thoracic and cardiovascular surgery
|October 27, 2023
概括
在患有结缔组织疾病 (CTD) 的儿科患者中,门节约根置换 (VSRR) 显示出良好的长期存活率. 需要对晚期的大动脉动脉瘤或剖析进行仔细监测,特别是在接受VSRR的年轻患者中.
科学领域:
- 心血管外科心血管外科
- 儿童心脏病学 儿童心脏病学
- 结合组织疾病 结合组织疾病
背景情况:
- 心血管干扰,特别是大动脉根扩张,是儿科连接组织疾病 (CTD) 的危及生命的并发症.
- 门节约根置换 (VSRR) 是这一群体中大动脉根扩张的外科选择.
研究的目的:
- 评估VSRR在儿童CTD患者的长期结果.
- 为了评估大动脉动脉瘤和VSRR之后的剖析再操作率.
主要方法:
- 对接受VSRR (2002-2021) 的儿科CTD患者的回顾性分析.
- 主要终点:综合所有死因和心血管再手术.
- 随访时间中位数为8.3年.
主要成果:
- 在24名儿科患者中,15年生存率为91.7% (平均年龄为14.4岁).
- 对于大动脉吐的再手术的10年累积发病率为15.6%;对于动脉瘤/剖析,它是29.1%.
- 手术时的年龄较小和13岁前的VSRR是不良事件的独立预测因素.
结论:
- 在儿科CTD中,VSRR提供了良好的长期存活率和低重复手术,用于大动脉吐.
- 晚些时候,大动脉动脉瘤或剖析可能会发生,需要保持警的监视.
- 接受VSRR治疗的年轻患者在随访期间需要特别注意.
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