耐火性逆流症状患者的功能食道疾病的发生频率在秘鲁利马,秘鲁
Luis Piza-Palacios1, Mercedes Cárdenas-Oña1, Ximena Vásquez-Ojeda1
1Medical School, Universidad Peruana Cayetano Heredia, Lima Peru.
概括
许多疑似非侵蚀性反流性疾病 (NERD) 的患者实际上有功能性胃灼热或食道过敏症. 这些功能障碍不是由酸性反流引起的,影响了本研究中超过86%的患者.
科学领域:
- 胃肠病学 胃肠病学
- 消化系统健康 消化系统健康
- 食道疾病 食道疾病
背景情况:
- 胃食道逆流性疾病 (GERD) 的管理往往在高达45%的患者中失败.
- 诊断内镜显示,大约70%的GERD疑似患者没有病变.
- 食道pH阻抗监测对于诊断病态酸暴露至关重要.
研究的目的:
- 确定疑似非侵蚀性逆流性疾病 (NERD) 患者食道过敏和功能性胃灼热的频率.
主要方法:
- 横截面研究分析pH阻抗和测力报告.
- 166名疑似NERD患者被纳入分析.
主要成果:
- 在86.15%的患者中诊断出功能障碍.
- 功能性胃灼热发生在46.9%的患者中,食道过敏发生在39.2%的患者中.
- 功能障碍的发生频率高于之前报告的.
结论:
- 在疑似NERD的患者中,功能障碍的高患病率,包括功能性胃灼热和食道过敏,存在.
- 年龄,心理状况,饮食和生活方式等因素可能会导致这些功能障碍的发展.
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