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中年男性的饮食脂肪质量和血清雄激素度

Miika M Wynne-Ellis¹, Jaakko J Mursu², Tomi-Pekka Tuomainen¹

¹University of Eastern Finland, Institute of Public Health and Clinical Nutrition, Kuopio, Finland.

European journal of clinical nutrition

|October 27, 2023

概括

饮食脂肪质量与男性雄激素水平没有独立联系. 然而,用和脂肪酸 (SFA) 代替蛋白质可能会增加丸激素和SHBG度.

科学领域:

内分泌学在内分泌学.
营养科学营养科学
男人的健康男人的健康

背景情况:

近几十年来,男性的平均丸激素度有所下降.
饮食脂肪质量的变化被假设会影响这些趋势.
了解饮食和雄激素之间的关系对于男性健康至关重要.

研究的目的:

调查不同饮食脂肪酸与男性血清雄激素度之间的关联.
探索和脂肪酸 (SFA),单不和脂肪酸 (MUFA),多不和脂肪酸 (PUFA) 和转化脂肪酸 (TFA) 对和SHBG水平的影响.
检查对等热量替代营养素和雄激素度的营养密度模型.

主要方法:

来自Kuopio缺血性心脏病风险因素研究的2546名男性 (平均年龄53岁) 的横截面研究.
用于评估脂肪酸摄入量和雄激素度的协差和线性回归分析.
多变量营养密度模型用于分析同热量营养替代效应.

主要成果:

较高的SFA摄入量最初与较高的总丸激素,自由丸激素和SHBG有关,而较高的PUFA摄入量与较低的度有关.
这些关联在对额外的混因素进行调整后变得无意义.
在MUFA或TFA摄入量和雄激素度之间没有发现显著的关联.
用SFA取代饮食蛋白质显示出与较高的总丸激素和SHBG的潜在关联.

结论:

饮食脂肪质量似乎与中年男性的血清雄激素度没有独立的关联.
用和脂肪酸 (SFA) 取代食蛋白可能与血清雄激素水平升高有关.

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