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Brain Imaging01:14

Brain Imaging

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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相关实验视频

Updated: Jul 12, 2025

Combining Behavior and EEG to Study the Effects of Mindfulness Meditation on Episodic Memory
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基于正念的随机对照试验导致大脑结构变化:一个解剖学概率元分析.

Savannah Siew1, Junhong Yu2

  • 1Psychology, School of Social Sciences, Nanyang Technological University, Singapore, Singapore. siew0051@e.ntu.edu.sg.

Scientific reports
|October 27, 2023
PubMed
概括

正念干预可以增加与注意力和疼痛处理相关的大脑区域的灰质体积. 这一元分析证实了结构性大脑变化,支持正念练习的长期益处.

科学领域:

  • 神经科学是一个神经科学.
  • 心理学 心理学 心理学

背景情况:

  • 正念干预越来越受欢迎,对其益处的研究越来越多.
  • 然而,关于随机控制的正念干预措施有效性的共识仍然难以捉摸.
  • 这项研究解决了需要理解与正念相关的结构性大脑变化.

研究的目的:

  • 通过元分析,研究在接受基于正念的干预的个体中的结构性大脑变化.
  • 为了确定受正念练习影响的特定大脑区域.
  • 探索结构变化与行为结果之间的关系.

主要方法:

  • 在Scopus,PubMed,Web of Science和PsycINFO进行了系统的文献搜索,直到2023年4月.
  • 包括11项随机对照试验 (RCT) 与581名参与者,评估整个大脑基于voxel的灰质或皮质厚度.
  • 解剖学概率估计 (ALE) 用于基于voxel的元分析,与灵敏度和行为分析.

主要成果:

  • 在右侧胰岛和前中心回旋 (MNI坐标:48,10,4) 中发现了增加灰质体积的显著集群.
  • 与对照组相比,这种大脑区域在正念干预组的体积增加 (p < 0.001,Z = 4.76,集群大小 = 632 mm3).
  • 行为分析将这种群体与注意力和somesthesis (疼痛) 处理联系起来.

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结论:

  • 正念干预诱导神经可塑性,特别是增加大脑注意力和疼痛调节关键区域的灰质体积.
  • 这些发现为正念的神经心理基础提供了证据.
  • 这项研究支持基于正念的干预措施对认知和感官处理的长期益处.