在癌和骨髓状细胞中调节HHLA2表达

Tomonari Shigemura1, Nahuel Perrot2, Zimo Huang2

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Ave., Boston, MA, 02215, USA.

BMC cancer
|October 27, 2023
PubMed
概括

人体内源性逆转录病毒-H LTR-关联2 (HHLA2) 在癌中的表达受到瘤微环境的调节. 在体内信号会在瘤中诱导HHLA2,但在体外并非如此,这凸显了对治疗开发的进一步研究的需要.

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