婴儿期可能预测自闭症谱系障碍的因素
Mina Gurevitz1, Gerry Leisman2,3
1Well Baby Clinic Physician, Maccabi Health Services, Herzliya 4649713, Israel.
Brain sciences
|October 28, 2023
概括
婴儿快速生长,出生时体重低,母亲年龄较大预测自闭症谱系障碍 (ASD) 的发展. 这些因素,以及两岁时的运动延迟,可能会将ASD增加与肥胖流行病和睡眠位置建议联系起来.
科学领域:
- 儿科 儿科 儿科
- 发育神经科学的发展神经科学.
- 公共卫生 公共卫生
背景情况:
- 全球自闭症谱系障碍 (ASD) 的患病率正在增加.
- 自闭症诊断增加的原因尚不清楚.
- 早期识别导致的因素对于理解自闭症至关重要.
研究的目的:
- 确定儿童自闭症谱系障碍 (ASD) 的早期促成因素.
- 为了分析产后记录,寻找ASD的预测性迹象.
- 调查环境因素与ASD发展之间的潜在联系.
主要方法:
- 追溯队列研究分析了1105名被诊断患有自闭症的儿童的产后记录.
- 将ASD病例与典型发育的儿童进行比较.
- 对出生和健康婴儿护理计划数据的统计分析.
主要成果:
- 婴儿体重,身高和头周长的快速增加预示着ASD的发展.
- 出生体重低,母亲年龄较大,体重/身高百分比在六个月后更高也预测ASD.
- 到两岁时,这些因素加上运动发育障碍预测ASD.
结论:
- 早期的快速生长和特定的早期生活因素与以后的ASD诊断有关.
- 研究结果表明,肥胖流行病,仰卧睡眠建议和ASD的异常大脑发育之间存在潜在联系.
- 需要进一步的研究来证实这些关联,并为预防策略提供信息.
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