在实用和语义语言处理和自闭症儿童认知能力期间的功能连接性之间的非典型关联
Amparo V Márquez-García1, Bonnie K Ng1,2, Grace Iarocci3
1Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
Brain sciences
|October 28, 2023
概括
患有自闭症谱系障碍 (ASD) 的儿童在语言任务中表现出不同的大脑连接能力,与典型发育的同龄人相比. 这些独特的神经模式可能是认知挑战的补偿机制.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 认知科学 认知科学
背景情况:
- 自闭症谱系障碍 (ASD) 与非典型的大脑连接和认知缺陷有关.
- 在ASD中,基于任务的脑活动与认知功能之间的联系尚不清楚.
研究的目的:
- 为了比较ASD儿童和典型发育 (TD) 儿童在语言任务期间的任务依赖性大脑连接.
- 在两组中调查大脑连接和认知能力之间的关系.
主要方法:
- 患有ASD和TD同龄人的儿童执行了语义和务实语言任务.
- 使用神经成像技术绘制了任务依赖的功能性大脑连接.
- 使用多变量统计数据将连接性与认知评估相关联.
主要成果:
- 两组都显示出大脑行为相关性,但这些关联的性质不同.
- 群体之间更大的功能连接差异与自闭症问卷,BRIEF,MSCS和SRS-2的更高分数相关.
- 较小的连接差异与WASI,实用语言和思维理论分数的差异相关.
结论:
- 患有自闭症的儿童在语言处理过程中表现出独特的神经通信模式.
- 这些独特的模式可能代表潜在的神经网络中断的补偿机制.
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