2D-Cine和3D-white体积测量的比较研究:揭示2D-Cine体积测量的系统性错误
Muhnnad Alkassar1,2, Sophia Engelhardt1, Tariq Abu-Tair3
1Department of Cardiac Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
Diagnostics (Basel, Switzerland)
|October 28, 2023
概括
与2D-cine方法相比,三维 (3D) 全心磁共振成像 (MRI) 体积测量为评估左心室 (LV) 体积和功能提供了更高的准确性. 这项研究强调了3D全心磁共振成像.
科学领域:
- 心血管成像 - 心血管成像
- 医学物理 医学物理
- 放射学 放射学是一门学科.
背景情况:
- 精确测量左心室 (LV) 体积对于评估心脏功能至关重要.
- 传统的2D-cine MRI方法可能会在体积计算中引入系统错误.
- 对比2D-cine和3D全心MRI对于优化心脏评估至关重要.
研究的目的:
- 直接比较来自2D-cine和3D全心MRI的体积测量结果.
- 调查这些方法对衍生功能参数的影响,例如中风体积 (SV).
- 在健康个体中,建立3D全心体积测量对2D-cine方法的优越性.
主要方法:
- 一项涉及18名健康参与者的前性研究.
- 同时获取2D-cine和3D全心MRI序列在透析末端和静脉末端.
- 直接比较两种方法之间的 LV 末端透缩体积 (EDV) 和末端静缩体积 (ESV).
- 从3D全心MRI与相对照MRI测量得出的功能参数的相关性.
主要成果:
- 在2D-cine和3D全心方法之间,在LV EDV和ESV中观察到最小的差异 (EDV的p < 0.01,ESV的p = 0.03).
- 通过2D-cine MRI对ESV的系统低估导致SV (5.6mL ± 2.6mL,p <0.01) 的显著高估.
- 来自3D全心MRI的功能计算显示出高精度和与相对比度测量有很强的相关性.
结论:
- 3D全心MRI体积测量优于2D-cine体积测量,用于准确评估LV体积和心脏功能.
- 2D-cine MRI测量容易出现系统错误,特别是在ESV估计中,导致不准确的SV计算.
- 这项研究提供了支持使用3D全心MRI进行更可靠的心脏功能评估的第一个证据.
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