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Updated: Jul 12, 2025

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非肌肉侵入性膀癌的体质突变与早期复发相关

Seong Hyeon Yu1, Sung Sun Kim2, Hyungki Lee3

  • 1Department of Urology, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju 61469, Republic of Korea.

Diagnostics (Basel, Switzerland)
|October 28, 2023
PubMed
概括

下一代测序确定了高瘤突变负担 (TMB) 和表皮生长因子受体 (EGFR) 和端粒酶逆转录酶 (TERT) 的突变,作为一年内非肌肉侵入性膀癌复发的关键预测因素.

关键词:
生物标志物 生物标志物基因检测 基因检测是指基因检测.这是下一代测序.泌尿膀的新生体是什么

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Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
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