儿童炎症性肠病的特征:克罗地亚单中心回顾性研究
Ivan Pivac1, Antonia Jelicic Kadic2, Ranka Despot2
1School of Medicine, University of Split, Soltanska 2, 21000 Split, Croatia.
Children (Basel, Switzerland)
|October 28, 2023
概括
克罗地亚的儿科炎性肠病 (IBD) 显示出克罗恩病 (CD) 的发病率更高,男性的诊断延迟更长. 在儿童的性结肠炎 (UC) 中,直肠出血更常见.
科学领域:
- 胃肠病学 胃肠病学
- 儿科 儿科 儿科
- 流行病学 流行病学
背景情况:
- 炎症性肠道疾病 (IBD),包括性结肠炎 (UC) 和克罗恩病 (CD),是经常在童年时被诊断出来的慢性疾病.
- 儿科IBD病例与成人发病病例相比,表现出不同的特征.
- 了解区域儿科IBD流行病学对于医疗保健规划至关重要.
研究的目的:
- 为了对克罗地亚的儿科IBD患者进行分析.
- 分析2012年至2021年间诊断的儿童IBD的人口,临床和流行病学特征.
- 在儿科人口中比较UC和CD之间的特征.
主要方法:
- 在斯普利特大学医院诊断的107名儿科IBD患者 (18岁以下) 的回顾性分析.
- 从2012年1月1日至2021年12月31日期间的住院诊断收集的数据.
- 分析包括患者人口统计学,症状持续时间,诊断延迟,发病率,BMIz-score和出现症状.
主要成果:
- 克罗地亚诊断出107例儿科IBD病例;55.1%的CD,43.9%的UC.
- 诊断时的平均年龄为14.1岁;男性占60.7%.
- 癌症患者的诊断延迟时间较长 (3.0个月对2.0个月);直肠出血在UC中更频繁 (72.3%对32.2%).
结论:
- 这项研究提供了克罗地亚儿科IBD十年的概况,突出了CD的主导地位和UC和CD之间的特定症状差异.
- 这些发现强调需要继续研究小儿IBD进展和该人口的管理.
- 建议进行进一步的前性研究,以阐明疾病轨迹,并优化克罗地亚儿童IBD的治疗策略.
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