水果袋消费与过敏疾病的早期表现没有关联
Emmy Fredriksson1, Stina Bodén1, Magnus Domellöf1
1Department of Clinical Sciences, Pediatrics, Umeå University, SE 90185 Umeå, Sweden.
Nutrients
|October 28, 2023
概括
婴儿期高摄入水果袋与增加过敏风险无关. 这项研究发现,水果袋摄入量与幼儿时代的过敏状况或敏感性之间没有联系.
科学领域:
- 儿科过敏和免疫学
- 胃肠道健康 胃肠道健康
- 营养流行病学 营养流行病学
背景情况:
- 婴儿食用酸性水果袋可能会损害胃肠上皮屏障,可能增加过敏风险.
- 以前的研究表明,水果袋摄入量和过敏发病率增加之间存在联系.
研究的目的:
- 调查高水果袋消费量与婴儿早期过敏表现之间的联系.
- 为了确定经常摄入水果袋是否与过敏表型或免疫球蛋白E (IgE) 敏感性相关.
主要方法:
- 在瑞典NorthPop出生队列研究中,分析了2959个亲子对象的数据.
- 评估9个月的果袋消费和18个月的过敏结果 (湿疹,喘息,喘,食物过敏).
- 在一个子组 (n=1792) 中测量18个月的血清IgE水平,以评估对食物和吸入剂混合物的敏感性.
主要成果:
- 9个月的每日水果袋消费显示出与吸入剂敏感性 (OR 2.27) 的初步关联,这在调整后的模型中失去了意义 (aOR 2.08).
- 果袋消费与过敏症状 (如湿疹,喘息,喘或食物过敏) 之间没有发现显著的关联.
- 果袋摄入量与18个月的IgE对食物或吸入剂混合物的敏感性无关.
结论:
- 婴儿时期的水果袋消费似乎与过敏表型或幼儿时期的IgE敏感性无关.
- 这些发现表明,人们对水果袋增加过敏风险的担忧可能无法得到当前证据的支持.
- 可能需要进一步的研究,以充分阐明婴儿饮食模式对过敏发展的长期影响.
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