将偏头痛与肠道疾病和慢性非传染性疾病联系起来
Manuela Di Lauro1, Cristina Guerriero1, Kevin Cornali1
1Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, RM, Italy.
Nutrients
|October 28, 2023
概括
偏头痛残疾与肠道失调有关,肠道细菌的不平衡. 营养和生活方式的改变可以恢复肠道健康,可能有助于偏头痛治疗.
科学领域:
- 神经学 神经学
- 胃肠病学 胃肠病学
- 微生物学 微生物学
背景情况:
- 偏头痛是成年人残疾的主要原因,其复杂的多因素起源.
- 肠道微生物群的不平衡,即肠道失调,越来越多地被认为是影响偏头痛等神经疾病的因素.
- 肠-大脑轴促进肠和中枢神经系统之间的通信,影响偏头痛的病理生理学.
研究的目的:
- 探索偏头痛和慢性非传染性疾病之间的双向关系.
- 审查肠道失调在偏头痛发育和进展中的作用.
- 突出营养和生活方式干预在管理偏头痛的潜力.
主要方法:
- 文献综述检查肠-大脑轴及其与偏头痛的联系.
- 对肠道失生症及其对神经系统疾病的影响研究的分析.
- 探索偏头痛,肠道健康和慢性疾病之间的相互作用.
主要成果:
- 肠道功能障碍是将偏头痛与慢性非传染性疾病 (如糖尿病,高血压,肥胖,癌症和慢性病) 联系在一起的常见因素.
- 通过饮食和生活方式调节肠道微生物群的组成,可以恢复肠道屏障的完整性并控制炎症性神经.
- 这些以肠道为重点的干预措施有望成为各种偏头痛亚型的辅助疗法.
结论:
- 肠道功能失调在偏头痛的病理生理学及其与其他慢性疾病的关联中起着重要作用.
- 针对肠道健康的营养方法和生活方式改变是偏头痛管理的可行治疗策略.
- 对肠-大脑轴的进一步研究对于开发全面的偏头痛治疗至关重要.
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