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脚骨折手术部位感染的发生率和危险因素:瑞典480名患者的观察性研究

Johanna Bergström¹, Emilia Möller Rydberg^1,2, David Wennergren^1,2

¹Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, 405 30 Gothenburg, Sweden.

Journal of clinical medicine

|October 28, 2023

概括

在瑞典,手术部位感染发生在10.2%的脚骨折手术中. 开放式骨折显著增加了SSI风险,金黄色葡萄球菌是最常见的病原体.

科学领域:

整形外科手术整形外科手术
传染病流行病学传染病流行病学
公共卫生公共卫生

背景情况:

手术部位感染 (SSI) 是足骨折手术后的一个严重并发症.
之前没有研究记录了瑞典的SSI发病率.
了解SSI对于改善患者的治疗结果和管理抗生素耐药性至关重要.

研究的目的:

为了确定瑞典骨骨折手术后SSI的发生率.
识别与SSI发展相关的风险因素.
确定导致SSI的最常见的细菌病原体.

主要方法:

480名接受初级脚骨折手术的患者的回顾性审查 (2017年9月 - 2019年8月).
数据收集包括潜在的SSI风险因素和临床结果.
统计分析使用了考克斯回归和描述性统计学.

主要成果:

整体SSI发病率为10.2% (49/480),其中7.3%是表面感染和2.9%是深层感染.
开放性骨折 (p < 0.001) 和患者年龄 (p = 0.016) 是显著的不变风险因素.
多变量分析证实开口骨折是唯一显著的风险因素 (HR = 3.0; p = 0.013).
金黄色葡萄球菌是最常见的病原体 (24.5%),甲基西林耐药率低 (4.1%).

结论:

确定的SSI发病率为10.2%,与国际数据一致.
感染监测对于打击全球抗生素耐药性至关重要.
需要进一步的前性研究来完善风险因素的识别和降低SSI费率.

关键词:

脚骨折脚骨折在脚上与骨折相关的感染.手术部位感染手术部位感染

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