人工智能增强分析揭示了孕产妇糖尿病对没有生长变化的胎儿皮下脂肪质量的影响
Hector Borboa-Olivares1, Johnatan Torres-Torres2, Arturo Flores-Pliego3
1Community Interventions Research Branch, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.
Journal of clinical medicine
|October 28, 2023
概括
孕产妇糖尿病,即使得到良好控制,也会增加胎儿皮下脂肪. 这种脂肪测量与其他因素一起,可以帮助预测新生儿的代谢并发症.
科学领域:
- 医学成像医学成像
- 胎儿医学 胎儿医学
- 医疗保健中的人工智能
背景情况:
- 患有糖尿病的孕妇经常经历胎儿生长受损.
- 预测未来的代谢并发症需要评估胎儿的身体组成,而不仅仅是简单的生长指标.
- 在怀孕期间控制良好的糖尿病仍然需要对胎儿发育影响进行调查.
研究的目的:
- 为了评估胎儿皮下脂肪组织的胎儿母亲的胎儿与控制得很好糖尿病.
- 使用3D超声波工具和断层超声波成像 (TUI) 进行可重复测量.
- 开发和验证人工智能 (AI) 模型,以评估胎儿脂肪测量的临床实用性.
主要方法:
- 使用3D超声波工具和离线断层超声波成像 (TUI) 分析.
- 在特定的胎儿段 (大腿骨和大腿骨) 中测量了皮下脂肪区域.
- 训练并验证了使用各种胎儿和母亲参数的三个AI分类器模型.
主要成果:
- 与对照组相比,患有糖尿病的母亲的胎儿表现出明显更大的皮下脂肪面积.
- 性能最好的AI模型包括皮下脂肪,妊娠年龄,胎儿体重,腹周,母亲的BMI和胎儿体重百分比.
- 最优的人工智能模型实现了70%的检测率,10%的错误阳性率和82%的积极预测值.
结论:
- 孕产妇糖尿病影响胎儿皮下脂肪组织,独立于胎儿整体生长.
- 胎儿皮下脂肪测量是预测代谢并发症的一个有价值的变量.
- 整合胎儿脂肪测量的AI模型在临床实用性方面显示出风险评估的前景.
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