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患有糖尿病的个体具有干眼现象型,由低症状负担和解剖学异常驱动
Elyana V T Locatelli1,2, Jaxon J Huang1,2, Simran Mangwani-Mordani1,2
1Surgical and Research Services, Miami Veterans Affairs Medical Center, Miami, FL 33125, USA.
Journal of clinical medicine
|October 28, 2023
概括
糖尿病会显著改变干眼病的现型,并发症导致的体征比报告的症状更多. 眼表面评估对于在糖尿病患者中检测眼睛干燥至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 糖尿病学 糖尿病学
背景情况:
- 干眼疾病 (DED) 包含各种不同的症状和迹象.
- 糖尿病 (DM) 和DED之间存在已知的关联,但具体的表型需要更深入的研究.
- 了解这种关系对于糖尿病人群中有效的DED管理至关重要.
研究的目的:
- 为了研究糖尿病和干眼疾病表型之间的关系.
- 为了比较不同组糖尿病及其并发症的和没有糖尿病的个体的干眼指标.
主要方法:
- 一项涉及366名患有DED症状或症状的退伍军人的前性,横截面研究.
- 参与者被分为三组:没有DM,没有末端器官并发症的DM和末端器官并发症的DM.
- 干眼指标包括问卷 (例如,眼皮表面疾病指数,疼痛量表) 和临床眼皮表面评估.
主要成果:
- 与其他组相比,患有DM和末端器官并发症的人报告了较少的DED和眼部疼痛症状.
- 眼松在DM与末端器官并发症组中明显更严重.
- 糖尿病的DED表型似乎更多是由临床症状驱动的,而不是主观症状.
结论:
- 糖尿病患者的干眼病现型的特点是身体症状,特别是眼异常,而不是明显的症状.
- 仅依靠基于症状的查可能会错过糖尿病患者的眼睛表面异常.
- 对于糖尿病患者,建议进行全面的裂灯检查,以检测眼睛表面疾病的迹象,包括解剖异常.
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