年龄和心血管风险因素对静脉神经炎的影响:回顾性队列研究
Guillermo Salib Coronel-Touma1, Chiara Monopoli-Roca1, Cristina Nicole Almeida-Ayerve1
1Department of Otorhinolaryngology-Head & Neck Surgery, Hospital Universitario de Salamanca, 37007 Salamanca, Spain.
Journal of clinical medicine
|October 28, 2023
概括
年龄显著影响前庭神经炎的恢复,特别是在55岁以上的患者中. 心血管风险因素并没有独立影响恢复,但高血压与年龄和性别相互作用.
科学领域:
- 神经学 神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 静脉管系统疾病 静脉管系统疾病
背景情况:
- 静脉神经炎 (VN) 是急性的常见原因.
- 了解影响VN康复的因素对于患者管理至关重要.
- 年龄和心血管风险因素 (CVRF) 在VN的长期结果中的作用需要进一步调查.
研究的目的:
- 分析年龄和CVRFs对前置神经炎 (VN) 演变的影响.
- 评估年龄和CVRFs对前庭眼反射 (VOR) 在VN患者中的影响.
主要方法:
- 追溯队列研究,包括63名越南患者.
- 患者根据CVRF的存在或不存在来分类.
- 通过视频头部脉冲测试 (vHIT) 测量平均VOR增益,在诊断和一年的随访时进行分析.
- 差异因子分析 (ANOVA) 用于评估年龄,性别和CVRFs对VOR增益的影响.
主要成果:
- 在CVRFs和没有CVRFs的患者之间没有观察到平均VOR增益的显著差异.
- 在年龄组之间发现了一年随访后平均VOR增长的显著差异:55岁以上的人为0.77 ± 0.20,55岁以下的人为0.87 ± 0.15 (p=0.036).
- 随机ANOVA显示,年龄组对VOR增长的显著主要影响在一年的随访中 (p=0.018).
- 在VOR增长上,性别,年龄组和高血压 (HTN) 之间的显著相互作用被确定 (p=0.043).
结论:
- 在随访期间,CVRFs不会独立地影响VN患者的平均VOR增长.
- 年龄是影响VOR增长的重要因素.
- 年龄对VOR增长的影响可能因性别和高血压的存在而改变.
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