焦点性活性结肠炎:它的临床影响是什么? 一个叙事审查
Emanuele Sinagra1, Francesco Vito Mandarino2, Marcello Maida3
1Gastroenterology and Endoscopy Unit, Fondazione Istituto G. Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy.
焦点性活性结肠炎 (FAC) 是一种经常在活检中看到的组织病理学发现. 本综述探讨了它在成人和儿童中的临床相关性,因为它的意义仍在争论中.
科学领域:
- 胃肠病学 胃肠病学
- 组织病理学 组织病理学
- 结肠直肠疾病 结肠直肠疾病
背景情况:
- 焦点活性结肠炎 (FAC) 是通过焦点中性粒细胞透到结肠密室来定义的.
- FAC诊断的临床意义受到争议,因为它通常是偶然发现的.
- 在结直肠活检中可以检测到FAC,而没有其他显微异常.
研究的目的:
- 审查焦点性活性结肠炎 (FAC) 的临床影响.
- 在成人和儿科人口中综合有关FAC的证据.
- 为了澄清FAC的诊断和预后价值.
主要方法:
- 现有科学文献的叙述性审查.
- 包括专注于成年人群的研究 (5项研究).
- 包括专注于儿科人口的研究 (两个研究).
主要成果:
- 关于FAC在成人中临床相关性的证据综合.
- 关于儿童FAC临床相关性的证据综合.
- 识别当前的辩论和知识差距.
结论:
- FAC的临床意义需要进一步调查.
- 区分偶然的FAC与临床相关的疾病至关重要.
- 需要更多的研究来确定FAC的明确诊断标准和患者管理策略.
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