揭开牙周炎和冠状病毒疾病之间的联系2019年:探索致病途径和临床影响
En-Chin Lin1, Yi-Chun Chiang1, Hsuan-Yu Lin1
1School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Biomedicines
|October 28, 2023
概括
牙周健康不佳可能会增加COVID-19感染风险,因为口腔组织表达ACE2受体. 虽然正在调查直接联系,但像IL-17这样的共享炎症途径表明了潜在的联系.
科学领域:
- 口腔健康 口腔健康
- 传染病 传染病 传染病
- 免疫学 免疫学 免疫学
背景情况:
- 牙周炎的特点是牙周组织的炎症和损失.
- 冠状病毒疾病2019 (COVID-19) 是由SARS-CoV-2引起的呼吸系统疾病,严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 进入由ACE2和TMPRSS2.2促进.
- 系统性健康状况不佳可能会加剧COVID-19.
研究的目的:
- 审查牙周炎和COVID-19之间的潜在关系.
- 探索疾病风险和严重程度的共同机制和影响.
主要方法:
- 对调查牙周炎和COVID-19的研究进行文献综述.
- 分析共享的分子通路,包括ACE2表达和互白素-17 (IL-17).
主要成果:
- 牙周口袋可能充当SARS-CoV-2的储存库,可能由于口腔粘膜中ACE2的表达而增加感染风险.
- 在这两种情况中都观察到升高的IL-17水平,可能有助于骨质再吸收.
- 目前,关于COVID-19对牙周健康的显著影响的证据不足,需要进一步的长期研究.
- 牙周炎和全身性疾病 (例如糖尿病) 之间的双向联系得到了认可,这可能会影响COVID-19的严重程度.
结论:
- 保持良好的口腔卫生和管理系统性疾病可能对减轻COVID-19风险和严重程度至关重要.
- 需要进一步的研究来阐明牙周炎和COVID-19之间的长期影响和精确机制.
相关概念视频
01:20COPD: Pathogenesis and Clinical Features
305
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
305
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.8K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.8K
01:29Pneumonia II: Pathophysiology
296
The pathophysiology of pneumonia involves the following steps:
296
01:20Infection
8.0K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
8.0K