可食用混合草本提取物对口腔微生物的抗菌作用:一个体外研究
Se-Eun Yun1, Byul-Bo Ra Choi1, Seoul-Hee Nam2
1Corporate Affiliated Research Institute, Feagle Co., Ltd., Yangsan 50561, Republic of Korea.
Medicina (Kaunas, Lithuania)
|October 28, 2023
概括
可食用的混合草本提取物有效地抑制口腔病原体,如Streptococcus mutans和Porphyromonas gingivalis. 这些天然抗微生物药物有望改善口腔健康并减少口臭.
科学领域:
- 口腔微生物学 口腔微生物学
- 自然产品化学 自然产品化学
- 抗菌剂 抗菌剂 抗菌剂
背景情况:
- 口腔内含有致病细菌,对口腔健康构成风险.
- 合成抗微生物药物在长期使用时可能会产生不良影响.
- 天然抗菌物质提供了潜在的替代品,副作用较少.
研究的目的:
- 评估可食用的混合草本提取物对口腔病原体的抗菌疗效.
- 评估这些提取物对细菌形态,粘附和口腔恶臭的影响.
主要方法:
- 混合草本提取物的制备和应用:斯基佐内佩塔 (Schizonepeta tenuifolia Briq,STB),孟塔 (Mentha piperascens,MP),阿坎托帕纳克斯 (Acanthopanax sessiliflorus Seem,AS) 和葡萄糖 (Glycyrrhiza uralensis,GU).
- 抗微生物活性测试,扫描电子显微镜进行形态分析,测量表面水性和减少口腔恶臭的测试.
- 使用配对的t测试进行统计分析.
主要成果:
- 通过混合植物提取物显著抑制了Streptococcus mutans,Enterococcus faecalis,Candida albicans和Porphyromonas gingivalis的生长 (p < 0.001).通过混合植物提取物显著抑制了Streptococcus mutans,Enterococcus faecalis,Candida albicans和Porphyromonas gingivalis的生长 (p < 0.001).通过混合植物提取物显著抑制了Streptococcus mutans,Enterococcus faecalis,Candida albicans和Porphyromonas gingivalis的生长 (p < 0.001).
- 观察到细菌细胞形态的改变和细菌粘附能力的降低 (p < 0.001).
- 挥发性硫化合物显著减少,这是口腔恶臭的主要原因 (p < 0.001).
结论:
- 可食用的混合草本提取物对关键的口腔病原体表现出强大的抗菌活性.
- 这些提取物有效地减少了细菌粘附和口腔恶臭.
- 研究结果表明,混合草本提取物是增强口腔卫生和健康的有希望的天然方法.
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