血清水平与慢性病患者的不安腿综合征之间的关系
Duygu Tutan1, Jan Ulfberg2, Nihal Aydemir3
1Department of Internal Medicine, Erol Olçok Training and Research Hospital, 19040 Çorum, Turkey.
Medicina (Kaunas, Lithuania)
|October 28, 2023
概括
这项研究发现,慢性病 (CKD) 患者的血清水平与不安腿综合征 (RLS) 之间没有联系. 慢性病阶段,特别是血液透析,与较高的RLS患病率有关,而不是水平.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 临床营养学 临床营养学
- 睡眠医学 睡眠医学
背景情况:
- 慢性病 (CKD) 是一个日益严重的全球健康问题,与严重的死亡率和发病率有关.
- 不安腿综合征 (RLS) 是慢性病患者常见的睡眠障碍,严重影响他们的生活质量.
- 以前的研究表明,低血清水平与末期脏疾病之间存在潜在联系.
研究的目的:
- 调查血清水平与慢性病患者不安腿综合征 (RLS) 患病率之间的关联.
- 在CKD患者中探索RLS和各种临床参数之间的潜在相关性.
主要方法:
- 一组46名慢性病患者被评估血清水平和不安腿综合征 (RLS) 的存在和严重程度.
- 在2020年1月至2022年2月期间,从门诊和透析单位招募患者.
- 排除标准包括年龄在18岁以下,有血液病/瘤病史或炎症状况;服用补充剂的患者也被排除在外. 统计分析包括描述性统计,相关性分析,曼·惠特尼U测试,学生的t测试和千平方测试.
主要成果:
- 在46名慢性病 (CKD) 患者中,34.78%的人患有不安腿综合征 (RLS).
- 与预透析和腹膜透析子组相比,在血液透析患者中,RLS的患病率显著更高 (p = 0.036).
- 在RSL和无RSL患者之间没有观察到血清水平的显著差异 (p = 0.327),尽管几个临床参数有显著差异.
结论:
- 在这组慢性病 (CKD) 患者中,血清水平与不安腿综合征 (RLS) 的存在或严重程度无关.
- 慢性病的阶段,特别是血液透析状态,成为影响RLS患病率的重要因素.
- 需要对更大患者群体进行进一步的前性研究,以确定CKD,RLS和潜在的促成因素之间的关系.
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