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益生菌在新生儿和儿童健康中的作用
Shanmugaprakasham Selvamani1,2,3, Nidhi Kapoor4, Arun Ajmera4
1Institute of Bioproduct Development, Universiti Teknologi Malaysia (UTM), Skudai, Johor Bahru 80000, Malaysia.
Microorganisms
|October 28, 2023
概括
益生菌,包括人乳寡糖 (HMO),支持婴儿肠道健康和免疫力. 本综述探讨了益生菌在儿童中的作用.
科学领域:
- 儿童营养学 儿童营养学
- 微生物组研究 微生物组研究
- 免疫学 免疫学 免疫学
背景情况:
- 益生菌因其健康益处而闻名,包括管理代谢,胃肠道和过敏状况.
- 人类牛奶寡糖化物 (HMO),是母乳中的关键益生菌,影响婴儿肠道微生物群和免疫发育.
- 婴儿配方奶粉越来越多地包含益生菌来模仿母乳养的好处.
研究的目的:
- 审查儿童前生物干预的功能性作用.
- 评估益生菌对微生物组成,过敏和功能性胃肠道疾病的影响.
- 评估合成HMO的有效性和安全性.
主要方法:
- 对儿科人口中益生菌干预研究的文献综述.
- 对母乳寡糖和它们的合成类似物进行的研究分析.
- 评估有关益生菌对儿童肠道微生物群,免疫系统和胃肠道健康的影响的数据.
主要成果:
- 益生菌,特别是HMO,在塑造婴儿肠道微生物群和免疫系统方面发挥着至关重要的作用.
- 合成HMO在复制母乳益生菌的有益作用方面表现有前途.
- 需要进一步的研究来证实合成HMO的长期安全性和有效性.
结论:
- 益生菌干预对于优化儿童肠道健康和免疫功能至关重要.
- 有针对性的益生菌使用,包括合成的HMO,为管理儿科健康状况提供了潜力.
- 对益生菌的有效性和安全性的持续研究对于临床应用至关重要.
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