酵母可以改善肠道屏障功能,通过改变断奶羔羊的肠道微生物群结构来减轻断奶压力
Yanjun Li1,2, Lulu Han2, Jie Liu2
1National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.
Microorganisms
|October 28, 2023
概括
酵母可以通过改善肠道健康和微生物结构来缓解羔羊的断奶压力. 补充显示了每日增益和料转换的积极趋势,这表明早期断奶羔羊的好处.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
背景情况:
- 早期断奶会引起羊羔的压力,对肠道形态,微生物平衡和整体健康产生负面影响.
- 酵母具有有益于动物健康的抗微生物,抗炎和抗氧化特性.
研究的目的:
- 研究酵母在减轻羊羔断奶压力的不良影响方面的功效.
- 分析酵母对羔羊生长,肠道完整性,免疫球蛋白水平和肠道微生物群的影响.
主要方法:
- 54只羔羊被分为三个组:母羊养 (ER),酵母处理 (AP) 和早期断奶 (EW).
- 评估的体重,干物质摄入量,每日增加,料转化率,免疫球蛋白水平,肠道形态和肠道微生物结构.
主要成果:
- 虽然体重和摄入量相似,但早期断奶减少了每日增益和料转化,酵母补充剂显示出积极的趋势.
- 早期断奶的羊羔显示出免疫球蛋白水平的显著变化以及肠道的高度和密室深度的有害变化.
- 没有观察到总体微生物群的丰富性或多样性的显著差异,但在酵母治疗组和早期断奶组之间观察到微生物结构的显著变化.
结论:
- 酵母显示出减轻羔羊的断奶压力的潜力,增长表现的趋势和肠道微生物结构的显著调节表明了这一点.
- 特定的细菌,如 * Lactobacillus * 和 * Aeriscardovia * 可能在调解酵母对断奶压力的好处方面至关重要.
- 这项研究提供了关于使用酵母来改善羊羔在关键的断奶期间通过肠道微生物组调节来改善羊羔健康的见解.
更多相关视频
相关概念视频
Yeast Signaling
14.7K
Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
14.7K
Mucosal Barrier of the Stomach
684
The gastric glands contain parietal cells that secrete hydrochloric acid (HCl) for digestion. The cells secrete HCl because it is highly corrosive and essential for breaking down food. To achieve this, they secrete hydrogen and chloride ions into the lumen of the gastric glands, which combine to form HCl.
Within parietal cells, carbonic acid is first formed through the reaction of water and carbon dioxide. The dissociation of carbonic acid releases bicarbonate and hydrogen ions. The bicarbonate...
Within parietal cells, carbonic acid is first formed through the reaction of water and carbon dioxide. The dissociation of carbonic acid releases bicarbonate and hydrogen ions. The bicarbonate...
684
Role of Ephrin-Eph Signalling in Intestinal Stem Cell Renewal
2.2K
Erythropoietin-producing hepatocellular carcinoma receptor (Eph) and its ligand, Eph receptor-interacting protein (Ephrin) were first discovered in the human carcinoma cell line, hence the name. Ephrin-Eph interaction guides cells to reach their appropriate location in adult tissues. They also play an essential role in the immune system by helping in immune cell migration, adhesion, and activation. Based on their structure and function, Eph is divided into two classes — EphA and EphB.
2.2K


