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Updated: Jul 12, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
10:28

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers

Published on: September 20, 2018

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通过表观遗传抑制SOX3,CELF2通过表观遗传抑制SOX3维持一个繁殖/OLIG2+质母细胞细胞表型

Laurent Turchi1,2, Nathalie Sakakini1, Gaelle Saviane1

  • 1CNRS, INSERM, Institut de Biologie Valrose, Team INSERM "Cancer Stem Cell Plasticity and Functional Intra-tumor Heterogeneity", Université Côte D'Azur, 06107 Nice, France.

Cancers
|October 28, 2023
PubMed
概括

针对CELF2,一种RNA结合蛋白,可能提供新的质母细胞瘤 (GBM) 治疗策略. 抑制CELF2可以降低具有攻击性的像干细胞的GBM细胞和瘤生长,从而有可能改善患者的治疗结果.

关键词:
这就是CELF2的意义.H3K9me3是什么意思 H3K9me3是什么意思在OLIG2中,OLIG2是OLIG2的前身.这是一种RNA结合蛋白.癌症干细胞是癌症干细胞.这是表观遗传学.质母细胞瘤 (glioblastoma) 是一种

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