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扩大弱亲和染色体的亲和范围,以识别针对膜蛋白的弱联体

Adrien Deloche1, François-Xavier Vidal1, Lucile Jammas2

  • 1Institut des Sciences Analytique, Universite Claude Bernard Lyon 1, ISA UMR 5280, CNRS, 5 Rue de la Doua, 69100 Villeurbanne, France.

Molecules (Basel, Switzerland)
|October 28, 2023
PubMed
概括

研究人员增强了弱亲和度色谱 (WAC) 来检测膜蛋白的非常低亲和度连接体. 这种基于片段的药物设计 (FBDD) 的进步扩大了识别新药候选者的能力.

关键词:
腺素受体的受体是什么?亲缘关系染色学 亲缘关系染色学基于碎片的药物发现.膜蛋白质是一种膜蛋白质.表面功能化的功能化.弱亲缘关系相互作用.

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