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自2010年以来在生物样本中酸盐和酸盐的预处理和分析方面的进展:一篇综述

Guojie Liu^1,2,3, Honghui Guo^2,3,4, Wanlin Zhao^2,3,4

¹Department of Chemistry, School of Forensic Medicine, China Medical University, Shenyang 110122, China.

Molecules (Basel, Switzerland)

|October 28, 2023

概括

在生物样本中精确测量酸盐和酸盐对于人类健康至关重要. 本综述涵盖了自2010年以来为精确检测而开发的先进的样本准备和分析方法.

科学领域:

分析化学分析化学
生物化学生物化学
环境科学环境科学

背景情况:

酸盐是氧化的关键代谢物,可以被摄入,其中酸盐是其代谢物.
准确和快速测量酸盐和酸盐对于评估人类健康状况至关重要.
现有的审查缺乏对生物样本的样本准备和分析方法的关注.

研究的目的:

审查和总结自2010年以来生物样本中酸盐和酸盐的样本制备和分析方法.
突出最近在化物和酸盐的同时测定方面的进展和未来前景.
解决在生物样本中检测低度和减轻矩阵干扰方面的挑战.

主要方法:

总结了各种样品预处理技术:液-液微提取,衍生,液-液提取,蛋白沉,固相提取和云点提取.
审查了分析方法,包括光谱,纸质设备,离子染色学,液体染色学,GC-MS,电化学,LC-MS和毛细血管电泳.
包括衍生试剂和提取方法的分析,具有高缩效率.

主要成果:

确定了许多有效的方法,用于样本制备和分析生物矩阵中的酸盐和酸盐.
强调使用单一分析方法同时确定酸盐和酸盐的重要性.
他注意到微流体技术的进步,以快速开发测试.

结论:

该综述提供了对生物样本中酸盐和酸盐分析近期发展的全面概述.
未来的研究应该专注于开发更快,更敏感和更强大的方法,特别是利用微流体技术.
对于可靠的健康评估,同时准确地确定两种分析物质至关重要.

关键词:

分析方法分析方法.生物样本是生物样本.酸盐酸盐的使用方法亚酸盐的化物样品处理处理方法

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