相关实验视频

Updated: Jul 31, 2026

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

Published on: August 28, 2015

开发含有精油的聚合物纳米囊作为皮肤输送系统:生物物理参数和皮肤动力学活体评估

Perla Giovanna Silva-Flores¹, Sergio Arturo Galindo-Rodríguez², Luis Alejandro Pérez-López³

¹Departamento de Embriología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.

Molecules (Basel, Switzerland)

|October 28, 2023

概括

从迷香和衣草中纳米封装精油 (EO) 增强了它们的抗氧化特性和皮肤沉积. 这些纳米封装EO (NC-EO) 为护肤应用提供了稳定,有效的替代方案.

科学领域:

化品科学化品科学
皮肤病学皮肤病学
纳米技术纳米技术

背景情况:

精油 (EOs) 是天然的抗氧化剂,具有潜在的皮肤益处.
欧的挥发性限制了它们在局部应用中的稳定性和有效性.
纳米封装提供了一种提高EO稳定性和皮肤停留时间的策略.

研究的目的:

为了纳米封装来自Rosmarinus officinalis和Lavandula dentata的精油.
评估纳米封装EO (NC-EO) 的抗氧化活性和皮肤传递潜力.
评估NC-EO对猪皮肤参数和皮肤动力学的ex vivo影响.

主要方法:

聚合物纳米囊 (NC-EO) 使用纳米沉方法制备.
抗氧化活性使用铁酸酸盐方法进行评估.
外体皮肤研究涉及生物工程技术,修饰的弗朗茨细胞和皮肤动力评估的带剥离.

主要成果:

纳米封装维持了EO的高抗氧化活性 (>65%).
与自由的EOO相比,NC-EOO在角层中的沉积得到了改善.
来自L. dentata的1,8-cineole在1小时内显示出较高的沉积率,与来自R. officinalis的相比.

结论:

纳米封装EO (NC-EO) 是一种稳定有效的抗氧化系统,可用于皮肤.
NC-EO可以提高活性化合物在皮肤中的沉积和停留时间.
这些发现支持使用NC-EO作为抗氧化剂护肤的可行替代品.

关键词:

拉文杜拉牙 (Lavandula dentata) 是一种有牙的植物.罗斯马林斯 (Rosmarinus officinalis) 是一种植物.纳米囊纳米囊的使用方法皮肤分娩皮肤分娩带剥离带剥离

更多相关视频

Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells

Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells

Published on: February 9, 2019

Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging

Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging

Published on: November 24, 2021

相关概念视频

Modified-Release Drug Delivery Systems: Site-Targeted

Modified-Release Drug Delivery Systems: Site-Targeted

Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...