咖啡粉中的咖啡酸作为MMP-9和DPP-4酶的双重抑制剂

Enade P Istyastono1, Nunung Yuniarti2, Vivitri D Prasasty3

  • 1Research Group of Computer-Aided Drug Design and Discovery of Bioactive Natural Products, Faculty of Pharmacy, Sanata Dharma University, Yogyakarta 55282, Indonesia.

PubMed
概括

咖啡酸和消耗咖啡粉提取物显示出抑制DPP-4和MMP-9酶的潜力,这些酶是治疗2型糖尿病和糖尿病足的关键标. 分子模拟揭示了关键相互作用,突出了它们的治疗前景.

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