相关实验视频

Updated: Jul 12, 2025

Plasmonic Photothermal Cancer Therapy: Nanoparticle-embedded Tumor-tissue-mimicking Phantoms for Visualizing Photothermal Temperature Distribution

Plasmonic Photothermal Cancer Therapy: Nanoparticle-embedded Tumor-tissue-mimicking Phantoms for Visualizing Photothermal Temperature Distribution

Published on: May 9, 2025

基于纳米载体的生物仿真光热疗法用于癌症治疗的最新进展

Juan Gallo¹, Aranzazu Villasante^2,3

¹Advanced Magnetic Theranostic Nanostructures Lab, International Iberian Nanotechnology Laboratory (INL), 4715-330 Braga, Portugal.

International journal of molecular sciences

|October 28, 2023

概括

仿生纳米粒子通过改善细胞向和生物相容性来增强癌症光热疗法 (PTT). 本综述探讨了将PTT从研究转化为临床应用的策略和挑战.

科学领域:

纳米医学是一种纳米医学.
生物材料科学生物材料科学
在瘤学瘤学.

背景情况:

光热疗法 (PTT) 使用可光激活的纳米粒子产生热量并诱导癌细胞死亡.
有效的PTT依赖于纳米粒子的光热转换效率和精确的细胞向.
目前的PTT在实现特定的蜂定位方面面临着挑战.

研究的目的:

审查在癌症治疗中设计PTT生物模拟光激活纳米载体的策略.
突出提高纳米载体的细胞向和生物相容性的进展.
讨论PTT的挑战和临床应用.

主要方法:

关于纳米医学和PTT策略的文献综述.
专注于仿生纳米粒子设计,以提高向性和生物相容性.
分析PTT翻译的挑战和当前的临床环境.

主要成果:

仿生纳米粒子提供了一个有希望的方法来克服PTT准的局限性.
纳米载体的功能化与自然材料特性增强生物相容性和免疫逃避.
为了创建有效的生物模拟光激活纳米载体,存在各种策略.

结论:

生物仿真纳米载体代表了针对向癌症PTT的重大进步.
解决转化障碍对于PTT的广泛临床采用至关重要.
对仿生设计的进一步研究可以优化PTT的有效性和安全性.

关键词:

生物模拟纳米粒子生物模拟纳米粒子癌症治疗治疗治疗癌症被膜伪装的纳米粒子.光热疗法是一种光热疗法.

更多相关视频

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

One Minute, Sub-One-Watt Photothermal Tumor Ablation Using Porphysomes, Intrinsic Multifunctional Nanovesicles

One Minute, Sub-One-Watt Photothermal Tumor Ablation Using Porphysomes, Intrinsic Multifunctional Nanovesicles

Published on: September 17, 2013

相关概念视频

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...