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Updated: Jul 12, 2025

A Chromatin Immunoprecipitation Assay to Identify Novel NFAT2 Target Genes in Chronic Lymphocytic Leukemia
09:52

A Chromatin Immunoprecipitation Assay to Identify Novel NFAT2 Target Genes in Chronic Lymphocytic Leukemia

Published on: December 4, 2018

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NF-κB通路的表达和激活与急性淋巴细胞白血病中甲酸耐药性和细胞增殖相关

Rafael Renatino Canevarolo1, Nathalia Moreno Cury1, José Andrés Yunes1,2

  • 1Centro de Pesquisa Boldrini, Centro Infantil Boldrini, Campinas 13083-210, SP, Brazil.

Genes
|October 28, 2023
PubMed
概括

研究人员探索了NF-κB途径与儿童急性淋巴细胞白血病 (ALL) 中的甲状腺素抗性之间的联系. 他们发现,通过NF-κB传递TNF-α信号通路对于MTX耐药性至关重要,尽管抑制它并不能完全解决耐药性.

关键词:
急性淋巴细胞白血病急性淋巴细胞白血病药物耐药性 耐药性 药物耐药性甲基特雷克萨酸盐的使用方法核因子卡帕 B B 核因子瘤丧亡因子α因子

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NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells10:57

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