CHA2DS2-VASC得分预测了冠状动脉血管检查患者的死亡率
Nicholay Teodorovich1, Gera Gandelman1, Michael Jonas1
1Kaplan Medical Center, Rehovot and the Hebrew University, Jerusalem 7661041, Israel.
Life (Basel, Switzerland)
|October 28, 2023
概括
CHA2DS2-VASc评分预测了接受冠状动脉血管学治疗的患者的死亡率. 较高的分数 (≥4) 独立表明死亡风险增加,建议在初始患者查中使用它.
科学领域:
- 心脏病学 心脏病学
- 临床风险分层的临床风险分层
背景情况:
- CHA2DS2-VASc评分是为了预测心房动 (AF) 中的血栓栓塞风险而建立的.
- 它在进行冠状动脉血管造影的患者的死亡率预测中的实用性尚未得到很好的定义.
研究的目的:
- 调查CHA2DS2-VASc得分在接受冠状动脉血管造影的患者中预测死亡率的能力.
主要方法:
- 对990名接受冠状动脉血管造影的患者进行前性研究.
- 根据CHA2DS2-VASc得分分层的患者 (<4对≥4).
- 卡普兰-梅尔分析和考克斯回归建模用于评估死亡风险.
主要成果:
- 一个CHA2DS2-VASc得分≥4与明显更高的全因死亡率 (38.7%对13.1%,p < 0.0001) 相关.
- 这种关联在各个子组中持续存在,包括那些有或没有AF的人,不同的LVEF和功能.
- 较高的CHA2DS2-VASc得分 (≥4) 是死亡率的一个独立预测指标 (HR 2.12,p = 0.001).
结论:
- CHA2DS2-VASc得分是一个简单可靠的预测器,用于预测冠状动脉血管造影患者的死亡率.
- 它可以用于初始查,以识别高风险个体.
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