在COVID-19之后,心脏瘤的高风险
Lubov Mitrofanova1, Igor Makarov1, Ekaterina Goncharova1
1Almazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Life (Basel, Switzerland)
|October 28, 2023
概括
这项研究表明,COVID-19与心脏瘤风险增加之间存在潜在联系,特别是心脏瘤. 在心脏瘤细胞中检测到SARS-CoV-2尖端蛋白,表明可能的趋势需要进一步调查.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 病毒学 病毒学
背景情况:
- 新出现的证据将严重的COVID-19与某些癌症的风险增加联系在一起.
- COVID-19和心脏瘤之间的潜在关联在很大程度上仍未被探索.
研究的目的:
- 为了调查COVID-19感染后患者心脏瘤发展的风险.
- 分析心脏瘤组织中SARS-CoV-2的存在.
主要方法:
- 对173个心脏瘤 (2016-2023) 的比较分析.
- 对21个心脏瘤进行了针对SARS-CoV-2尖端蛋白,CD34和CD68的免疫组织化学和免疫光检查.
- 分析包括肌肉瘤,乳头纤维肌肉瘤,肌肉纤维肌肉瘤和肌肉肌肉瘤.
主要成果:
- 预计到2023年,心脏瘤的病例将增加1.5倍,心脏瘤的病例将大幅增加.
- 在11个后COVID瘤中的10个中检测到SARS-CoV-2尖端蛋白在瘤细胞,内皮细胞和巨细胞中.
- 没有发现与疫苗接种的相关性;在流行前和流行后的瘤患者之间没有显著的人口差异.
结论:
- 在心脏组织中SARS-CoV-2的持久性表明,在COVID-19幸存者中心脏瘤增加的潜在趋势.
- 流行病后心脏瘤,特别是瘤的增加需要进一步的研究.
- 这项研究强调需要继续调查COVID-19对心血管健康的长期影响.
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