风湿性关节炎和肺癌的同时发生 - 巧合还是不巧合?
Ioana Munteanu1,2, Constantin Gheorghevici2, Catalin Constantin Coca2
1Faculty of Medicine, Titu Maiorescu University, 040441 Bucharest, Romania.
Life (Basel, Switzerland)
|October 28, 2023
概括
接受甲状腺素治疗的类风湿性关节炎患者面临肺癌风险增加. 一个案例研究强调了由于误解胸痛为风湿性而延迟诊断如何导致晚期支气管肺癌.
科学领域:
- 在瘤学瘤学.
- 类风湿病学 类风湿病学
- 肺部病理学 肺部病理学
背景情况:
- 支气管肺癌是全球癌症死亡率的主要原因之一.
- 风湿性关节炎和甲状腺素使用是肺癌的已知的危险因素.
- 早期识别症状对于有效治疗肺癌至关重要.
研究的目的:
- 呈现一个病例的晚期肺癌在风湿性关节炎患者治疗甲状腺酸盐.
- 强调风湿病和肺癌的重叠症状所带来的诊断挑战.
- 为了突出考虑患有持续性胸痛的类风湿性关节炎患者的恶性病变的重要性.
主要方法:
- 一个80岁的前吸烟者患有类风湿性关节炎的病例报告.
- 临床表现包括渐进的咳,呼吸不全和胸痛.
- 诊断程序涉及成像 (CT扫描) 和超声波导向的胸前肺部活检.
主要成果:
- 影像检查显示,这是一颗巨大的肺瘤,有顶膜侵袭和肋骨溶解.
- 组织病理学证实了侵袭性状细胞肺癌,G2.
- 由于诊断延迟,患者出现呼吸衰竭.
结论:
- 胸部疼痛,误认为是风湿性疼痛,显著延迟了肺癌的诊断.
- 这一案例强调了在风湿性关节炎患者中诊断肺癌时需要保持警.
- 在这个患者群体中,迅速评估呼吸系统症状对于预防晚期疾病和呼吸系统衰竭至关重要.
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