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玻璃离子体水泥复合材料的化物释放和可充电性

Sudarat Wongphattarakul¹, Rungroj Kuson¹, Thanapat Sastraruji²

¹Department of Prosthodontics, Faculty of Dentistry, Chiang Mai University, Chiang Mai 50200, Thailand.

|October 28, 2023

概括

新开发的多聚 (乳酸) 复合材料显示出抗原潜力. 玻璃离子水泥复合材料提供可重复的化物可充电性,用于长期的牙重矿化.

科学领域:

生物材料科学生物材料科学
牙科材料科学牙科材料科学
聚合物科学聚合物科学

背景情况:

牙损仍然是一个重要的全球健康问题.
开发有效的抗菌原材料对于预防至关重要.
聚乳酸 (PLA) 复合材料为药物输送和组织工程应用提供了潜力.

研究的目的:

为了研究新型抗癌性聚乳酸复合材料的化物释放,可充电性和降解.
为了比较含有玻璃离子体水泥 (GIC) 的PLA复合材料与化 (NaF) 的性能.
评估这些材料对长期牙再生矿物的潜力.

主要方法:

使用溶剂造制备了含有不同度的GIC和NaF的聚乳酸复合材料.
随着时间的推移,化物释放和可充电性得到了评估.
分析了体外降解,吸水和表面形态 (SEM).

主要成果:

所有测试的复合材料都表现出化物释放,其中PLA/NaF的初始释放率最高.
化物水平保持在重矿化 (0.030.53 ppm) 的有效范围内.
与PLA/NaF不同的是,PLA/GIC复合材料证明了可重复的化物可充电性.
与PLA/GIC和对照相比,PLA/NaF复合材料在降解过程中显示出更高的重量变化和水的吸收.

结论:

新开发的聚乳酸/玻璃离子体水泥 (PLA/GIC) 复合物显示出作为抗菌原材料的显著前景.
PLA/GIC的可重复的化物可充电性确保其具有持续治疗效果的潜力.
PLA/GIC复合材料是开发先进牙科修复和预防材料的可行选择.

关键词:

抗原物质是一种抗原物质.化物补充充电可以使用.化物释放可以释放化物.玻璃离子体水泥的玻璃离子体聚乳酸) 是一种乳酸.

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