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在巴西中部Goiânia的脆弱人群中,E型肝炎的流行率
Sheila Araújo Teles1, Karlla Antonieta Amorim Caetano1, Megmar Aparecida Dos Santos Carneiro2
1Faculty of Nursing, Federal University of Goias, Goiania 74605-080, Brazil.
Viruses
|October 28, 2023
概括
肝炎E病毒 (HEV) 感染在巴西中部弱势群体中不常见. 这项研究发现,在可回收垃圾收集者,移民,难民,无家可归者和LGBTQ+个人中,过去和最近的HEV感染的血清流行率较低.
科学领域:
- 病毒学 病毒学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 肝炎E病毒 (HEV) 感染是一个全球性的健康问题.
- 易受伤害的人群可能面临感染性疾病的风险增加.
- 关于巴西中部脆弱群体中HEV流行情况的数据有限.
研究的目的:
- 在巴西戈亚尼亚市的脆弱人群中确定肝炎E病毒 (HEV) 感染的血清流行率.
- 评估过去 (IgG) 和最近 (IgM) HEV感染的流行率.
主要方法:
- 一项涉及472名弱势群体 (可回收垃圾收集者,移民,难民,无家可归者,LGBTQ+个人) 的横向研究.
- 血清样本使用化学发光免疫测试测试抗HEV IgG和IgM抗体.
- 实时聚合酶连锁反应 (PCR) 用于检测阳性样本中的HEV RNA.
主要成果:
- 观察到抗HEV IgG (过去感染) 的血清流行率为0.87%.
- 抗HEV IgM (最近感染) 检测到只有一个人 (0.22%),他是HEV RNA负的.
- 在这个人群中,发现HEV感染很少发生.
结论:
- 在巴西中部的易受伤害的个体中,HEV感染并不常见.
- 该研究表明,研究组中过去和最近的HEV感染的血清流行率较低.
- 可能需要进一步的研究来了解特定易受伤害的子组中的HEV流行病学.
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