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Updated: Jun 14, 2026

Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection
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一种RNA-Scaffold蛋白子单位疫苗用于鼻腔免疫接种

Joy-Yan Lam1,2, Wan-Man Wong1,2, Chun-Kit Yuen1,2

  • 1Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

Vaccines
|October 28, 2023
PubMed
概括

一种新型的自我辅助蛋白-RNA疫苗通过鼻子输送,有效诱导对呼吸道病毒的免疫力. 这种方法产生了强大的粘膜和全身免疫反应,为未来的疫苗开发提供了有前途的战略.

关键词:
在RNA架构上,RNA架构是RNA架构.这就是SARS-CoV-2病毒.粘膜免疫力 粘膜免疫力鼻接种疫苗 鼻接种疫苗蛋白质亚单元疫苗的疫苗.自己补充的自我补充剂

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RNA Structure01:23

RNA Structure

Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA): messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three RNA types consist of a...
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RNA Polymerase II Accessory Proteins

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...
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RNA Polymerase II Accessory Proteins

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Respiratory Syncytial Virus Disease

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