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Updated: Jul 12, 2025

Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans
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一个短的可以防止与年龄相关的蛋白质毒性

Hassan Elsana1, Reut Bruck-Haimson2, Huadong Zhu2

  • 1The Lautenberg Center of Immunology and Cancer Research, The Institute for Medical Research Israel - Canada (IMRIC), The Hebrew University School of Medicine, Jerusalem, Israel.

Aging cell
|October 28, 2023
PubMed
概括

一种新型的五氨基酸 (5MER) 在模型生物中有效降低与阿尔茨海默氏症和亨廷顿病相关的蛋白质聚合物的毒性. 这种对开发神经退行性疾病的新疗法充满希望.

关键词:
C. 优雅的 优雅的老化的老化 衰老的老化神经退行症的神经退行症蛋白质稳定性 蛋白质稳定性通过陪伴者传递信号.

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