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Updated: Jul 12, 2025

Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques
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甘氨酸和链对IgG1 Fc中的动态的影响

Christina Bergonzo1, J Todd Hoopes2, Zvi Kelman1,2

  • 1Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology, The University of Maryland, Gudelsky Way, Rockville, MD, USA.

Journal of biomolecular structure & dynamics
|October 28, 2023
PubMed
概括

IgG1抗体的可结晶片段 (Fc) 域对于药物开发至关重要. 了解链和甘氨酸结构如何影响Fc稳定性和动态对于设计有效的抗体疗法至关重要.

关键词:
分子动力学分子动力学结晶学 结晶学是指结晶学.相互作用的自由能量.葡萄糖酶化是什么? 葡萄糖酶化是什么?这是一种单克隆抗体.蛋白质结构 蛋白质结构

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