延长DMT的心理和生理影响
Lisa X Luan1, Emma Eckernäs2, Michael Ashton2
1Centre for Psychedelic Research, Division of Psychiatry, Department of Brain Sciences, Imperial College London, London, UK.
Journal of psychopharmacology (Oxford, England)
|October 28, 2023
概括
这项研究引入了一种新的方法,用于延长N,N-Dimethyltryptamine (DMT) 经验,使用连续IV输液. 这种新型的药物在长时间的迷幻效应方面被证明是安全有效的,为进一步的研究铺平了道路.
科学领域:
- 神经科学是一个神经科学.
- 心理药理学 心理药理学
背景情况:
- N,N-Dimethyltryptamine (DMT) 是一种强有力的血清性迷幻药,可以诱导短暂的改变意识状态.
- 迪姆的独特效果为研究意识和治疗心理健康状况提供了潜力.
研究的目的:
- 研究一种持续静脉注射 (IV) DMT的新方法,以延长其主观效应的持续时间.
- 评估长时间暴露于DMT的安全性和耐受性.
主要方法:
- 这是一项受试者内部,安慰剂控制的研究,涉及11名健康志愿者.
- 一个新的给药方案,结合了玻尿酸注射和DMT的恒定速率输注.
- 剂量方案是根据药理动力学数据推导出来的,以保持稳定的血度30分钟.
主要成果:
- 持续的IVDMT方法有效地以稳定和可容忍的方式延长了迷幻体验.
- 主观效应保持不变,而焦虑仍然很低,心率习惯化,表明安全性.
- 对DMT的急性心理耐受性随着主观影响的平稳而发展,尽管血度上升.
结论:
- 持续的IVDMT给药是安全和有效的延长迷幻体验.
- 这种方法为长时间的DMT暴露提供了稳定且可容忍的方法.
- 这些发现支持用于基础和临床研究应用的连续IVDMT的发展.
关键词:
迷幻药物是一种精神药物.亚亚瓦斯卡 (Ayahuasca) 是一种意识 意识 意识 意识 意识这是一种二甲基三胺 (dimethyltryptamine).血清胺 (serotonin) 是一种神经元.更多相关视频
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