动物MetaOmics:用于探索动物微生物基因组和微生物组的多omics数据资源
Ruirui Hu1, Fulin Li1, Yifan Chen2,3
1College of Life Sciences, Shihezi University, Shihezi, Xinjiang 832003, China.
Nucleic acids research
|October 28, 2023
概括
动物Meta-omics景观数据库提供了广泛的微生物组数据,包括各种动物物种的基因组,基因功能和蛋白质信息. 本资源有助于探索动物微生物群的分类和功能多样性.
科学领域:
- 微生物学 微生物学
- 生物信息学是一种生物信息学.
- 基因组学就是基因组学.
背景情况:
- 动物微生物对宿主健康和功能至关重要.
- 需要全面的数据整合来理解动物微生物群落.
- 现有的资源缺乏跨多种动物物种的综合多omics数据.
研究的目的:
- 建立一个集中的,可自由访问的动物元组学数据数据库.
- 为探索动物微生物组的组成,功能和活动提供一个用户友好的平台.
- 促进对动物微生物群的分类,多样性和功能基因的研究.
主要方法:
- 综合的元基因组,元转录组和元蛋白组数据分析.
- 来自广泛的动物物种的微生物基因组的注释.
- 在动物微生物组内分析基因表达和蛋白质识别.
- 开发一个用户友好的接口来检索和分析数据.
主要成果:
- 来自581种动物 (细菌,病毒,古生物,真菌) 的55898个微生物基因组进行了注释.
- 分析了321个元转录原子和326个元蛋白原子数据集.
- 描述了679种细菌和13种古生物的泛基因组学动态和组成.
- 数据库提供了对物种,基因组,活动水平,蛋白质功能和泛基因组组成的访问.
结论:
- 动物Meta-omics景观数据库是动物微生物组研究的宝贵资源.
- 它可以有效地探索各种动物宿主中的微生物群落.
- 该数据库支持更深入地了解微生物分类,功能多样性和生物过程.
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